|
چکیده
|
The diaryl hydroxy methyl group has become an integral part in the development of the synthesis of many compounds. Though itself not stereogenic, this structural unit has become the backbone of many chiral auxiliaries, drugs, chemicals, flavors and materials used in the agricultural industry, ligands, as well as catalysts with the two flanking aryl groups playing a pivotal role in maintaining or enhancing the stereoselectivity1. also used for the kinetic resolution of racemic α-aryl propanoic acids, α-aryl butanoic acids and β-substituted α-aryl propanoic acids 2. The catalytic activity of palladium nanoparticles explained in various reactions, Separable nanomagnetic organometallic catalysts were synthesized by different processes through direct immobilization of phosphine ligand on Fe3O4 magnetic nanoparticles bearing metallic catalyst direct immobilization of palladium salt on Fe3O4 bearing phosphine ligand 3,4. In this research, these heterogeneous nanomagnetic catalysts preceded the addition of arylboronic acids 2 to aromatic 1 aldehydes for C-C bond formation reactions with considerable excellent activity to synthesis of diaryl hydroxy methyl 3 in 30 minutes. These catalysts were easily recovered by the simple magnetic decantation and reused with no significant decrease in the activity (Scheme 1). The structure of products are investigated by melting point, FT-IR, 1H NMR and 13C NMR spectroscopies. Also the structure of nanomagnetic organometallic catalysts by FT-IR, VSM, TGA-DTA, TEM, SEM, EDAX and X-ray diffraction (XRD).
|