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چکیده
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Nowadays, chiral nanoligands act a great role in the synthesis of optically active compounds that are used in the production of pharmaceutical precursors . For the preparation of these nanomagnetic ligands, magnetic nanoparticles Fe3O4 (MNPs) were widely used as support owing to facile separation, non-toxically effects, and highly recyclable and reusable properties .As well as, chiral amines play an important role in biological activities and agricultural, natural, and pharmaceutical products. They are important intermediates in the synthesis of some drugs and chemicals and act as important ligands in the synthesis of chiral compounds. Therefore, the development of chiral amines synthesis methods such as the addition reactions on imines has attracted the attention of chemists . In this work, in order to develop an innovative approach, we synthesize chiral amines 3 via C-C bond formation by addition of boron reagent 2 to aldimines 1 in the presence of recoverable and reusable chiral phosphine nanoligands supported on MNPs that complexed with Pd metal
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