مشخصات پژوهش

عنوان	A simple and expedient method for the stepwise synthesis of 2-ethoxy-(4H)-3,1-benzoxazine-4-ones
نوع پژوهش	مقاله چاپ‌شده در مجلات علمی
کلیدواژه‌ها	2-Ethoxy-(4H)-3,1-benzoxazine-4-ones, Diethyl dicarbonate, Cyanuric chloride, N,N'-Dicyclohexylcarbodiimide, Dehydrocyclization reagent
چکیده	A simple and practical route is described for the synthesis of 2-ethoxy-(4H)-3,1-benzoxazine-4-ones using the coupling reaction of anthranilic acid derivatives with diethyl dicarbonate following with fast cyclization of the carbamate adduct with a dehydrocyclization agent such as cyanuric chloride and N,N'-dicyclohexylcarbodiimide in PEG at room temperature. High yields of the products obtained under mild reaction conditions with simple work-up of the reaction mixture.
پژوهشگران	مهناز شرفی (نفر سوم)، ئه سرین بهمنی (نفر دوم)، فرزاد نیک پور (نفر اول)