مشخصات پژوهش

عنوان	Multimode Waveguide Evanescent field Fluorescence Microscopy: Measurement of Cell-Substratum separation Distance
نوع پژوهش	مقاله چاپ‌شده در مجلات علمی
کلیدواژه‌ها	Waveguide, Fluorescence Microscopy, Evanescent Field, Osteoblastic Cells, Langmuir–Blodgett Films, Cell-Substratum Separation Distances
چکیده	Waveguide evanescent field fluorescence microscopy allows imaging of thin films and contact regions between biological cells and their substratum. On changing the propagating waveguidemode exciting the fluorescence markers, the normalized evanescent field intensity at a specific distance from the waveguide surface is modified. This enables the determination of thin film thickness and cell-substratum separation distances. An extensive analysis of multimodeion-exchanged waveguides is presented, focusing on their applications as substrata for studying interfacial phenomena. The experimental results on Langmuir–Blodgett films are in excellent agreement with the simulations. For osteoblastic cells, close contacts were observed. © 2009 American Institute of Physics.
پژوهشگران	سیلویا میتلر (نفر چهارم)، س. جفری دیکسون (نفر سوم)، Souzan Armstrong (نفر دوم)، عبدالله حسن زاده (نفر اول)