مشخصات پژوهش

عنوان	Synthesis of Chiral Nano Heterogeneous Catalysts by Immobilization of Chiral (S)-2-amino-2-phenylethanol and (S)-2-amino-3-phenylpropanol Ligands on Nanoporous Silica MCM-41 and Their Applications in Enantioselective Kharasch-Sosnovsky Reaction
نوع پژوهش	مقاله ارائه شده کنفرانسی
کلیدواژه‌ها	Chiral Heterogeneous catalysts, Kharasch-Sosnovsky reaction, Chiral allylic ester.
چکیده	Heterogeneous catalysts have attracted a lot of attention in comparison to other catalysts due to their ability to reuse them through recovering and easy separation . A method for preparation of a practical heterogeneous catalyst is to immobilize the chiral amino alcohol ligands on nanoporous silica MCM-41. Enantioselective Kharasch-Sosnovsky reaction can be used as one of the most considerable synthetic methods for the preparation of highly functionalized olefins such as allylic esters and allylic alcohols that are important intermediates in the synthesis of compounds that are used in the preparation of pesticides and pharmaceutical compounds. For this purpose, MCM-41 was prepared and modified by (3-chloropropyl) trimethoxy silane. Afterward, the chiral amino alcohols (S)-2-amino-2-phenylethanol and (S)-2-amino-3-phenylpropanol which are synthesis by reducing their corresponding amino acids, immobilized on MCM-41 mesoporous silicas. Then copper complexes of these chiral ligands for the first time were examined in the asymmetric allylic C-H bond oxidation of cycloolefins. The chiral allylic esters were achieved in good yields and enantioselectivities . The catalyst could be easily recovered and reused fifth times without remarkable loss of the reactivity, yield, and enantioselectivity.
پژوهشگران	شادی کمانگر (نفر اول)، سعدی صمدی (نفر دوم)