مشخصات پژوهش

عنوان	Copper-Catalyzed C–S Bond Formation via the Cleavage of C–O Bonds in the Presence of S8 as the Sulfur Source
نوع پژوهش	مقاله چاپ‌شده در مجلات علمی
کلیدواژه‌ها	phenolic esters, arylboronic acid, triphenyltin chloride, copper salt, catalyst, sulfides
چکیده	Useful and applicable methods for one-pot and odorless synthesis of unsymmetrical and symmetrical diaryl sulfides via C–O bond activation are presented. First, a new efficient procedure for the synthesis of unsymmetrical sulfides using the cross-coupling reaction of phenolic esters such as acetates, tosylates, and triflates and with arylboronic acid or triphenyltin chloride as the coupling partners is reported. Depending on the reaction, S8/KF or S8/NaOt-Bu system is found to be an effective source of sulfur in the presence of copper salts and in poly(ethylene glycol) as a green solvent. Then, the synthesis of symmetrical diaryl sulfides from phenolic compounds by using S8 as the sulfur source and NaOt-Bu in anhydrous DMF at 120 °C under N2 is described. By these protocols, the synthesis of a variety of unsymmetrical and symmetrical sulfides become easier than the available protocols in which thiols and aryl halides are directly used for the preparation of the sulfides.
پژوهشگران	ساجده قیصر زاده (نفر پنجم)، محمد قلی نژاد (نفر چهارم)، آرش قادری (نفر سوم)، امین رستمی (نفر دوم)، عابد رستمی (نفر اول)