عنوان
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Isocyanide-based multicomponent reactions: synthesis of 3,3-dicyano-N-alkyl-2-arylpropanamide derivatives
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نوع پژوهش
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مقاله چاپشده در مجلات علمی
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کلیدواژهها
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Isocyanide, 3,3-Dicyano-N-alkyl-2-arylpropanamide, Multi-component reactions, Malononitrile
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چکیده
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A new isocyanide-based multicomponent reaction between an aromatic aldehyde, malononitrile, an isocyanide, and acetic acid efficiently provides 3,3-dicyano-N-alkyl-2-arylpropanamide derivatives in excellent yields in ethanol at 70 C. This reaction led to the construction of two carbon–carbon bonds and one amide group in a single synthetic step.
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پژوهشگران
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سعدی صمدی (نفر سوم)، محسن زینالی (نفر دوم)، ابراهیم سلیمانی (نفر اول)
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