مشخصات پژوهش

عنوان	Highly Regioselective and Diastereoselective, One-Pot, Four-Component Synthesis of Novel Spiroindenoquinoxalineindolizidine Derivatives
نوع پژوهش	مقاله چاپ‌شده در مجلات علمی
کلیدواژه‌ها	spiroindenoquinoxalineindolizidines,Highly Regioselective, Diastereoselective,stereochemistry, 1,3-dipolar cycloaddition, azomethine ylides
چکیده	A one-pot, four-component procedure for the synthesis of novel spiroindenoquinoxalineindolizidines with high regioselectivity and diastereoselectivity from the 1,3-dipolar cycloaddition of azomethine ylides, generated from indenoquinoxalines and pipecolinic acid, and chalcones is described. The reaction occurs under reflux of ethanol as a green solvent and in the absence of any catalyst. The cycloadducts are obtained purely without future purification. The regiochemistry and stereochemistry of resultant cycloadducts have been determined by several 2D-NMR spectroscopic techniques and X-ray single crystal diffraction.
پژوهشگران	سعدی صمدی (نفر سوم)، بهروز نوتاش (نفر ششم به بعد)، خسرو جدیدی (نفر پنجم)، فربود صلاحی (نفر چهارم)، عبدالحمید آروین نژاد (نفر دوم)، مهدی مومنی (نفر اول)