مشخصات پژوهش

صفحه نخست /A simple approach to the ...
عنوان A simple approach to the synthesis of highly functionalized 3-alkylidene-2,3-dihydro-1H-Pyrrole-2-ol derivatives and related pyrroles
نوع پژوهش مقاله چاپ‌شده در مجلات علمی
کلیدواژه‌ها Acetylenic esters  Dibenzoylacetylene  Enaminones  Pyrroles
چکیده The reaction of various primary amines with acetylenic esters at ambient temperature in THF/H2O (50:50) produced related enaminones. Subsequently reaction of these in situ prepared enaminones with dibenzoylacetylene leads to 3-alkylidene-2,3-dihydro-1H-pyrrol-2-olderivatives in good yields. The reaction of these products with various alcohols in the presence of a catalytic amount of HCl produced highly functionalized pyrroles in nearly quantitative yields.
پژوهشگران کوروش پوردوایی (نفر دوم)، فاروق نصیری (نفر اول)