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عنوان
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Perspectives on new opportunities for nano-enabled strategies for gene delivery to plants using nanoporous materials
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نوع پژوهش
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مقاله چاپشده در مجلات علمی
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کلیدواژهها
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Agrobacterium, CRISPR, Nano-system delivery, Plant transformation, nanoporous
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چکیده
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Genetic engineering has improved the quality and quantity of crops by introducing desired DNA sequences into the plant genome. Traditional transformation strategies face constraints such as low transformation efficiency, damage to plant tissues, and genotype dependency. Smart nanovehicle-based delivery is a newly emerged method for direct DNA delivery to plant genomes. The basis of this new approach of plant genetic transformation, nanomaterial-mediated gene delivery, is the appropriate protection of transferred DNA from the nucleases present in the cell cytoplasm through the nanocarriers. The conjugation of desired nucleic acids with engineered nanocarriers can solve the problem of genetic manipulation in some valuable recalcitrant plant genotypes. Combining nano-enabled genetic transformation with the new and powerful technique of targeted genome editing, CRISPR (clustered regularly interspaced short palindromic repeats), can create new protocols for efficient improvement of desired plants. Silica-based nan
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پژوهشگران
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محسن نیازیان (نفر اول)، ایوب ملااحمدنالوسی (Ayoub Molaahmad Nalousi) (نفر دوم)، پژمان آزادی (نفر سوم)، لیلا مامنی (نفر چهارم)، استفن چندلر (نفر پنجم)
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