مشخصات پژوهش

عنوان	Identifying crossing collagen fibers in human corneal tissues using pSHG images
نوع پژوهش	مقاله چاپ‌شده در مجلات علمی
کلیدواژه‌ها	Identifying crossing, collagen, fibers, human corneal, SHG, pSHG
چکیده	Polarization sensitive second harmonic generation (pSHG) microscopy has been used previously to characterize the structure of collagen fibers in corneal samples. Due to the typical organization of the corneal stroma, the information that pSHG provides may be misleading in points where two different collagen fiber bundles orient along different direction crossings. Here, a simulation that illustrates the problem is presented, along with a novel method that is capable of identifying these crossing points. These results can be used to improve the evaluation of corneal collagen structure, and it has been applied to analyze pSHG data acquired from healthy and keratoconic human corneal samples
پژوهشگران	ریتا منچوچی (نفر پنجم)، مارکو لومباردو (نفر چهارم)، جوزپه لومباردو (نفر سوم)، مهدی علیزاده (نفر اول)، پابلو لوزا آلوارز (نفر ششم به بعد)، داوید مورینو (نفر دوم)، مسعود قطبی (نفر ششم به بعد)