مشخصات پژوهش

عنوان	Novel pyridinedicarboxamide derivatives and a polymeric complex: synthesis, structural characterization, electrochemical behavior, catalytic and cytotoxic studies
نوع پژوهش	مقاله ارائه شده کنفرانسی
کلیدواژه‌ها	pyridinedicarboxamide,copper(II)
چکیده	Multidentate heterocyclic ligands of pyridylcarboxamides have an important position in biochemistry and coordination chemistry. [1]. Metal ions with capability of substituting for amidic hydrogen can coordinate strongly to the amide group [2]. A large number of high-valence copper complexes with amide-based ligands were investigated as biomimetic models and catalytic oxidants [4]. These results, along with our interest to design new compounds with catalytic and cytotoxic activity, led us to synthesize and study of new amidic ligands from the reaction of pyridine-2,6-dicarboxylic acid and 2-aminobenzoic acid and also, a Cu(II) complex from (L1) (Scheme 1) [5]. It is noteworthy that despite high stability of amide groups [6], X-ray studies exhibited that one of the amidic bonds was hydrolyzed during the complexation of ligand (L1) [7] and an unsymmetrically polymeric Cu(II) complex was synthesized. In this paper, possible mechanisms and some effective factors on the hydrolysis of amides are discussed.
پژوهشگران	سارا عبدالمالکی (نفر اول)، محمد قادرمزی (نفر دوم)