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Title
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Guanidinum Chloride as Dehydrocyclization Agent in the Synthesis of 2-Fuctionalized (4H)-3,1-Benzoxazine-4-ones
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Type
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JournalPaper
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Keywords
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2-Ethoxy-(4H)-3,1-benzoxazine-4-one, 2-(ethyl carboxylate)-(4H)-3,1-benzoxazine-4-ones, Guanidium chloride, Dehydrocyclization agent, Green conditions
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Abstract
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A facile and expedient route for the synthesis of 2-ethoxy- and 2-(ethyl carboxylate)-(4H)-3,1-benzoxazine-4-ones is described using guanidinium chloride as a safe and convenient dehydrocyclization agent. High yields of the products obtain under mild reaction conditions without need to use of any catalyst and with easy work-up of the reaction mixture.
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Researchers
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havasi frogh (Third Researcher), Mahnaz Sharafi (Fourth Researcher), bahmani asrin (Second Researcher), Farzad Nikpour (First Researcher)
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