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Title An Efficient Approach for the Synthesis of N-Phenylcarboxamido-2-aryl-1,2-dihydro-(4H)-3,1-benzoxazine-4-ones
Type JournalPaper
Keywords 1,2-Dihydro-3,1-benzoxazin-4-ones; Anthranilic acid; Phenyl isocyanate; Schiff base; Cyclization reaction
Abstract An efficient synthesis of N-phenylcarboxamodo-2-aryl-1,2-dihydro-(4H)-3,1-benzoxazin-4-ones is described by cyclization reaction of some 2-(benzylidene-amino)-benzoic acids with phenyl isocyanate under reflux conditions in CHCl3. High yields of the products obtained in high purity with simple work-up.
Researchers Farzad Nikpour (Second Researcher), Sharmin Irani (First Researcher)