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Title A Green, Facile, and One-pot Synthesis of 2,4-(1H,3H)-Quinazolinediones under Microwave Irradiations
Type JournalPaper
Keywords Quinazoline-2,4-diones; microwave irradiations; one-pot synthesis; anthranilic acid derivatives; environmentally friendly; one-pot synthesis
Abstract Quinazoline-2,4-diones are of considerable interest due to their wide pharmacological properties. Here, we have described an environmentally friendly method for the one-pot synthesis of 2,4(1H,3H)-quinazolinediones from the reaction of anthranilic acid derivatives with urea in H2O media under microwave irradiations. This method is simple, safe and fast which produces high yield of products without use of any catalyst.
Researchers Touraj Paibast (Second Researcher), Farzad Nikpour (First Researcher)