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Title
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Electrochemically Catalyzed N–N Coupling and Ring Cleavage Reaction of 1H-Pyrazoles
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Type
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JournalPaper
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Keywords
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electrocatalysis, electrosynthesis, cyclic voltammetry, N–N coupling reaction, pyrazole ring cleavage
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Abstract
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The electrocatalyzed N–N coupling and ring cleavage reaction of 3-methyl-, 3,5-dimethyl-, 3-methyl-5-phenyl- and 3,5-diphenyl- 1H-pyrazole was investigated and led to the electro-organic synthesis of new heterocyclic compounds. The results revealed that electrochemically produced 1H-pyrazoleox plays the role of acceptor in a reaction with the starting molecule via a N–N coupling and ring cleavage reaction of pyrazoles. The proposed reaction sequence consists of anodic oxidation, dimerization, rearrangement and reduction. The electrochemically catalyzed reactions were accomplished under constant-current and constant-potential conditions using an undivided electrochemical cell with the advantages of mild reaction conditions, remarkable yields and environmental compatibility.
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Researchers
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Farzad Nikpour (Third Researcher), Mahnaz Sharafi (Second Researcher), Sara Zandi (First Researcher)
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