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Title
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A one-pot, three-component synthesis of thiazolidine-2-thiones
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Type
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JournalPaper
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Keywords
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,Thiazolidine-2-thione, Regiospecific, Iodocyclization, Dehydrohalogenation, Nucleophilic substitution
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Abstract
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An efficient method for the synthesis of thiazolidine-2-thiones is described via regiospecific iodocyclization of an allyl amine, carbon disulfide, and iodine. Dehydrohalogenation of the iodo-derivatives gives thiazole-2(3H)-thiones. In addition, nucleophilic substitution of the iodine in the products is accomplished using NaN3, thiophenol, or dithiocarbamate.
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Researchers
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Akram Ashouri (Third Researcher), Katayoun Marjani (Second Researcher), Azim Ziyaei-Halimehjani (First Researcher)
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