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Title Synthesis of Novel Chiral Diamino Alcohols and Their Application in Copper-Catalyzed Asymmetric Allylic Oxidation of Cycloolefins
Type JournalPaper
Keywords Chiral diamino alcohols, Chiral hydroxyldiamides, Asymmetric allylic oxidation, Small chiral libraries, Chiral pool amino acids
Abstract The small library of new enantiomerically pure (S,S)-diamino alcohols 1 and their hydroxyldiamide precursors 2 were conveniently synthesized on a gram scale from inexpensive and commercially chiral pool amino acids. The catalytic and induced asymmetric effects of the chiral ligands 1 in the asymmetric allylic oxidation of cycloolefins were investigated.
Researchers Laleh Faraji (First Researcher), Saadi Samadi (Second Researcher), Behrouz Notash (Fourth Researcher), Khosrow Jadidi (Third Researcher)