|
Title
|
Novel magnetic nanoparticles Fe3O4-immobilized domino Knoevenagel condensation, Michael addition, and cyclization catalyst
|
|
Type
|
JournalPaper
|
|
Keywords
|
Magnetic nanoparticles, Guanidine, Basic nanocatalyst, Knoevenagel condensation, Chromene derivatives
|
|
Abstract
|
The synthesis, characterization and applications of guanidine supported on magnetic nanoparticles Fe3O4 (MNPs–Guanidine) as a novel magnetically separable base nanocatalyst are described. We have studied the application of this new catalyst for the Knoevenagel condensation reaction of aromatic aldehydes with malononitrile or cyanoacetate in PEG/water = 1:1 at room temperature. Also, the three-component and one-pot synthesis of 2-amino-4H-chromenes and 2-amino-4H-benzo[h]chromenes by condensing al-dehydes, malononitrile and cyclic 1,3-dicarbonyl/α-naphthol, in the presence of catalytic amount of MNPs–Guanidine under same conditions is investigated. The supported catalyst could simply be separated and recovered from the reaction mixture with the assistance of an external magnet and reused several times
|
|
Researchers
|
Hoshyar Gholami (Third Researcher), bahareh atashkar (Second Researcher), Amin Rostami (First Researcher)
|