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Title One-Pot Synthesis of 3-Aminoquinazoline-2,4-diones
Type Presentation
Keywords 3-Aminoquinazoline-2,4-diones; semicarbazide hydrochloride; One-pot Synthesis.
Abstract Here, we have described for the first time,the synthesis of a series of 3-amino-2-4-quinazolinediones with various substitutions on aromatic rings.They have been prepared by reaction of anthranilic acid derivatives with semicarbazide hydrocholoride in DMF under reflux condition. The reaction was carried out in one-pot, without use of catalyst.
Researchers Samira Kazemi (Third Researcher), Davood Sheikh (Second Researcher), Farzad Nikpour (First Researcher)