Chirality has been one of the most important topics in the field of applied sciences, including medicine, pharmacy, environment, etc. Chiral compounds have different enantiomers, which usually have different biological activities and pharmacological properties. One way to access one of the enantiomers of chiral compounds is asymmetric synthesis and the use of chiral catalysts. Many catalysts have been designed and synthesized for this purpose, among which oxazoline-based ligands have very high catalytic capabilities and, as a class of efficient and powerful ligands, are increasingly and very seriously involved in asymmetric transformations. synthesis of chiral allylic esters is among the most important of these transformations [1-4]. These compounds are important intermediate and structural units in bioactive and medical molecules [5]. There are well-known methods to access these chiral compounds, but an interesting and rare reaction could be a combination of two well-known reactions involving the dehydrogenation of alkanes and the allylic oxidation of alkenes simultaneously [6, 7]. There is also no report on the use of chiral catalysts in this type of reaction to induce chirality. An efficient class of chiral bisoxazoline ligands were synthesized and purified through several steps and their structures were confirmed by 1H NMR and 13C NMR spectroscopic techniques . Finally, they were used as chiral catalysts for the synthesis of chiral allylic esters via simultaneous dehydrogenation and enantioselective allylic oxidation of unactivated cycloalkanes due to their greater availability and lower cost compared to the corresponding cycloalkanes in the presence of copper salts. Chiral allylic esters were obtained in high yields and moderate to good enantioselectivity.
