The optimal weight training intensity to improve body composition in overweight men is unclear. The purpose of this study was to determine the effect of 12 weeks of high intensity versus moderate intensity weight training of equal work output on body composition in overweight men (BMI = 25-29.9 kg/m 2 ). Twenty sedentary men (age: 27 ± 0.5 year; Body weight: 84 ± 1.43 kg; BMI: 28.23 ± 1.11 kg/m) were randomized in two equal groups (n = 10): 1) moderate intensity exercise (MI; 5sets*6reps [60% (1RM-1repetition maximum)]; and 2) high intensity exercise (HI; 5sets*6reps [85% 1RM]). The weight training program was performed 3d.w . Relative body fat (% BF) was assessed by a skin-fold caliper. Significant differences between and within the groups were analyzed using a two-way split-plot analysis of variance (ANOVA). Statistical significance was accepted at p<0.05. The two-way ANOVA showed statistically significant differences between HI and MI groups, therefore, the Scheffe Post-Hoc Test showed that there was a significant decrease (p<0.05) in the relative body fat (BF) (D = 27%), percent of body fat (%BF) (22%), BMI (D = 9.34%), and body weight (BW) (D = 6.51%) in the HI group during the course of the study than in the MI group Also, comparison of means between the pre/post test showed statistically significant decreases in skinfold thickness (HI = 45%, p = 0.001; MI = 25%, p = 0.02), percent of body fat (HI = 41%, p = 0.001; MI = 23%, p = 0.04), BMI (HI = 21.5%, p = 0.001; MI = 13.7%, p = 0.03), and body weight (HI = 21.58%, p = 0.001; MI = 13.82%, p = 0.01) after participation in a 12-week weight training program. It is concluded that 12 weeks of HI weight training may be more effective in improving body composition than MI weight training in overweight young men with physical characteristics similar to the ones found in the present study.