Methyl orange (MO) as one of azo dyes group is a toxic substance that harms human health and the environment. Therefore, it is very necessary to treat MO before discharged into environment. In this study titanium dioxide (TiO2) nanotube was fabricated using anodizing process. Then copper oxide was electrodeposited on TiO2 nano tube to synthesis Ti/TiO2-CuO as efficient electrocatalyst. The prepared Ti/TiO2-CuO used as anode for electrochemical removal of MO. Field emission scanning electron microscopy (FESEM) confirmed the successful formation of TiO₂ nanotubes, while X-ray diffraction (XRD) analysis verified their anatase phase. The Response Surface Methodology (RSM) was applied to optimize key factors affecting MO removal, including initial MO concentration, applied current, and initial pH. At the optimum conditions including MO concentration of 67.6 mg/L, applied current of 8.55 mA, and initial pH of 6, the MO removal efficiency reached to 96.8 %. Additionally, kinetic analysis indicated that the MO removal process followed a second-order reaction model.
