Abstract This study examined the mediation role of perceived social support in the association between hope and health-related quality of life with coronavirus anxiety in the elderly. The research was conducted by descriptive method with a structural equations design. The population included all the over-60 elderly individuals residing in Sanandaj city, Iran, in 2021. Among them, 220 individuals were selected through available sampling method. To gather the data, the questionnaires of coronavirus anxiety, perceived social support, hope and health-related quality of life were used. Data analysis was conducted by using structural equations modeling and via SPSSv23 and AMOSv26 software. Data analysis indicated that there is a significant and negative relationship between hope, health-related quality of life, and perceived coronavirus anxiety among the elderly. Moreover, perceived social support plays a mediating role in the relationship of both hope and health-related quality of life with coronavirus anxiety. The present study provided an important insight regarding the mediating role of perceived social support in the relationship of hope and health-related quality of life with coronavirus anxiety the elderly. Through creating programs to hold suitable interventions for improving perceived social support, the COVID-19–related anxiety can be reduced during its prevalence.
