The Lineweaver-Burk equation, as the first linear derivative of the Michaelis-Menten fundamental equation, opened the way for several other equations, to determine the kinetic parameters of enzymes, especially the Michaelis constant Km and the maximum reaction speed Vmax. But not only this derivative but also none of the other derivatizations reached an equation that could directly give the Km and Vmax of the studied enzyme from the graphs equation. Here, a new equation is derived from the Michaelis-Menten equation, which fulfills the above purpose, and it is possible to directly and without any additional math operations determine the Km and Vmax values from the equation of the linear graph. The equation is [S0] = Vmax[S0]/V0 - Km.
