Introduction: Today, education as a program and its role in increasing the effectiveness and improving the intellectual and vocational level of staff is of most interest to managers. The aim of this study was to evaluate the effectiveness of e-learning method compared to traditional methods on empowering nurses. Method: This cross-sectional study was conducted on 402 nurses who had attended in electronic and traditional training courses the data collection tool was a standard training effectiveness questionnaire. Data were analyzed using SPSS software, version 21 and by chi-square tests, Fisher and Unpaired-Test. Findings: the level of Proficiency and practice between electronic and traditional teaching methods was significant (p<0.05), but the scale of the access and reaction was not significant (p>0.05). There was no significant difference(p>o.o5)in terms of empowerment in both electronic and traditional teaching methods, significant sense, sense of competence, a sense of choice and self-efficacy, but within the sense of participation was a significant difference between both methods(p<0.05). Conclusion: E-learning can be used as traditional teaching methods and in some areas even be used effectively to provide continuing education programs. Therefore, it is suggested to be considered as an effective teaching method in medical universities and related hospitals
