The most dangerous landslide disasters always cause serious economic losses and human deaths. The contribution of this work is to present an integrated landslide modelling framework, in which an adaptive neuro-fuzzy inference system (ANFIS) is combined with the two optimization algorithms of whale optimization algorithm (WOA) and grey wolf optimizer (GWO) at Anyuan County, China. It means that WOA and GWO are used as two meta-heuristic algorithms to improve the prediction performance of the ANFIS-based methods. In addition, the step-wise weight assessment ratio analysis (SWARA) method is used to obtain the initial weight of each class of landslide influencing factors. To validate the effectiveness of the proposed framework, 315 landslide events in history were selected for our experiments and were randomly divided into the training and verification sets. To perform landslide susceptibility mapping, fifteen geological, hydrological, geomorphological, land cover, and other factors are considered for the modelling construction. The landslide susceptibility maps by SWARA, SWARA-ANFIS, SWARA-ANFIS-PSO, SWARA-ANFIS-WOA, and SWARA-ANFIS-GWO models are assessed using the measures of the receiver operating characteristic (ROC) curve and root-mean-square error (RMSE). The experiments demonstrated that the obtained results of modelling process from the SWARA to the SAWRA-ANFIS-GWO model were more accurate and that the proposed methods have satisfactory prediction ability. Specifically, prediction accuracy by area under the curve (AUC) of SWARA, SWARA-ANFIS, SWARA-ANFIS-PSO, SWARA-ANFIS-GWO, and SWARA-ANFIS-WOA models were 0.831, 0.831, 0.850, 0.856, and 0.869, respectively. Due to adaptability and usability, the proposed prediction methods can be applied to other areas for landslide management and mitigation as well as prevention throughout the world. View Full-Text