Evapotranspiration assessment is one of the most substantial issues in hydrology. The methods used in modelling reference evapotranspiration (ET0) consist of empirical equations or complex methods based on physical processes. In arid and semi-arid climates, determining the amount of evapotranspiration has a major role in the design of irrigation systems, irrigation network management, planning and management of water resources and water management issues in the agricultural sector. This paper presents a case study of five meteorological stations located in Kurdistan province in the west of Iran. The ability of three different soft computing methods, an artificial neural network (ANN), an adaptive neuro-fuzzy inference system (ANFIS) and gene expression programming (GEP), were compared for modelling ET0 in this study. The FAO56 Penman−Monteith model was considered as a reference model and soft computing models were compared using the Priestley−Taylor, Hargreaves, Hargreaves−Samani, Makkink and Makkink−Hansen empirical methods, with respect to the determination co-efficient, the root mean square error, the mean absolute error and the Nash–Sutcliffe model efficiency co-efficient. Soft computing models were superior to the empirical methods in modelling ET0. Among the soft computing methods, the ANN was found to be better than the ANFIS and GEP.