Mitochondrial dynamic is involved in cell cycle. Previous studies have been shown the relation between mitochondrial dynamic processes and progress of various type of cancer. Mammals have mfn2 gene, which is involved in mitochondrial membrane fusion. Cancer is a disease characterized by inappropriate cell growth. In this study, breast cancer and non- cancerous breast tissue was taken for investigation of mfn2 gene expression by Real- time PCR method. the result of this study showed a signification decrease in mfn2 gene expression in tumor tissue compared to the non- cancerous breast tissues (p<0.01)
