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Title Reaction between alkyl isocyanides and dimethyl acetylenedicarboxylate in the presence of polyhydroxybenzenes. Synthesis of 4H-chromene derivatives
Type JournalPaper
Keywords 4H-chromene; alkyl isocyanides; acetylenic ester; OH-acids
Abstract The reactive intermediate generated by the addition of alkyl isocyanides to dimethyl acetylenedicarboxylate was trapped by phenols such as resorcinol, catechol, hydroquinone, pyrogallol, 2,4-dihydroxybenzaldehyde, or 8-hydroxyquinoline to produce highly functionalized 4H-chromenes in fairly good yields
Researchers Farough Nasiri (Third Researcher), Hoorieh Djahaniani (Second Researcher), yavari Issa (First Researcher)