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Title Chemo- and stereoselective reaction between alkyl isosyanides and dimethyl 1,3-acetonedicarbocxylate in the presence of acetylenic esters
Type JournalPaper
Keywords 2-Amino-4H-pyrans · Enaminones · Alkyl isocyanides · Acetylenic esters · CH acids
Abstract The reaction of alkyl isocyanides with dimethyl 1,3-acetonedicarboxylate in the presence of dialkyl acetylenedicarboxylates in CH2Cl2 at ambient temperature leads to highly functionalized 2-amino-4H-pyrans and 1,2-dialkyl 4,6-dimethyl-(1E, 3E)-3 (alkylamino)-5-oxo-1,3-hexadiene- 1,2,4,6-tetracarboxylates.
Researchers koroush pourdavaee (Third Researcher), Fatemeh Nazem (Second Researcher), Farough Nasiri (First Researcher)