Research Info

Title	Adipokine modulation in obesity: Evaluating the integrative impact of chlorella vulgaris supplementation and interval resistance training in obese males
Type	JournalPaper
Keywords	LeptinAdiponectinNeuregulin-4Metabolic syndrome Exercise training Obese Adults
Abstract	Aims To evaluate the effects of 12-week chlorella vulgaris (CV) combined with interval resistance training (IRT) on plasma levels of leptin, adiponectin and neuregulin-4 (Nrg-4) in obese men. Methods Obese men (n = 44, BMI of 32.1 ± 1.5 kg/m2) were randomly allocated to the following groups of 11 participants per group: Control Placebo group (CP), CV supplement group (CV), Interval Resistance Training group plus Placebo (IRT + P), and Interval Resistance Training plus CV supplement group (IRT + CV). IRT was performed three times a week for 12 weeks using three sets of 10 repetitions at 60 % 1RM, and integrating an active rest interval with 15 repetitions at 20 % 1RM. Participants consumed either CV (1800 mg daily) or a placebo. Pre- and post-intervention blood samples were obtained to assess adipokines which were measured by ELISA. Results While CV or IRT separately did not alter plasma levels of leptin (p > 0.05), their combination reduced leptin levels (p = 0.007). IRT and IRT plus CV increased the plasma levels of adiponectin and Nrg-4 (p < 0.01). An intergroup comparison indicated significant elevations of adiponectin and Nrg-4 in the CV compared to the CP group (p < 0.05). Conclusion The combination of IRT and CV modulates plasma levels of leptin, adiponectin and NRG4 more effectively than either IRT or CV separately in obese men.
Researchers	Hassane Zouhal (Not In First Six Researchers), Ismail Laher (Not In First Six Researchers), Anthony C. Hackney (Not In First Six Researchers), Mark E.T. Willems (Not In First Six Researchers), Ayoub Saeidi (Fifth Researcher), Saeed Daneshyar (Fourth Researcher), Raheleh Amadeh Juybari (Third Researcher), Nastaran Javadi Behzadi (Second Researcher), Maryam Delfan (First Researcher)