Raheleh Shakeri

Education

BSc. in Biology- Zoology , Razi University , Iran (2002 - 2006)
Thesis title:
PhD. in Biochemistry , University of Tehran , Iran (2010 - 2015)
Thesis title: Investigating the preservation of auto-inhibited form of human Apaf-1 using site directed mutagenesis in glutamate 546
MSc. in Biochemistry , University of Tehran , Iran (2007 - 2010)
Thesis title: Screening of algae extracts isolated from Iranian soil and chemical compounds for caspase-9 and XIAPBIR3 inhibition

Courses

Bachelor Of Science

Biochemistry: Structure

Master Of Science

Structure of Biological Macromolecules

Biochemistry of Proteins and Nucleic Acids

.row3_default .coursesList .courseAcademicLevelContent { opacity: 1; position: static; height: initial; } .row3_default .coursesList .courseWrapper .courseAcademicLevelTitle { visibility: visible; font-family: Arial; font-size: 1.3rem; transition: background-color .5s, color .5s; display: block; float: left; color: rgb(102, 102, 102); background-color: rgb(255, 255, 255); direction: ltr; text-align: left; padding: .5% 2%; cursor: pointer; border-radius: 5%; margin-top: 1%; }

Research activities

Journal Papers

Essential Oil of Hymenocrater longiflorus Benth. as a Pro-Apoptotic Agent in Human Breast Cancer Cells Pashiv Mohammadi, Raheleh Shakeri, Maliheh Safavi, Jalal Khorshidi, Negin Chinjoo (2024)

Induced ultrasensitive electrochemical biosensor for target MDA-MB-231 cell cytoplasmic protein detection based on RNA-cleavage DNAzyme catalytic reaction Rahman Hallaj, Zhaleh Ghafary, Osamah Saleh Hamah Kariem, Raheleh Shakeri (2023)

Untargeted Metabolomics Analysis of Crocus cancellatus subsp. damascenus (Herb.) B. Mathew Stigmas and Their Anticarcinogenic Effect on Breast Cancer Cells Raheleh Shakeri, Bahram Savari, Mahsa Naghavi Sheikholeslami, Tayebeh Radjabian, Jalal Khorshidi, Maliheh Safavi (2022)

Contribution of Apaf-1 to the pathogenesis of cancer and neurodegenerative diseases Raheleh Shakeri, َAsma Kheirollahi, Jamshid Davoodi (2021)

In vitro antioxidant and antidiabetic activity of essential oils encapsulated in gelatin‐pectin particles against sugar, lipid and protein oxidation and amylase and glucosidase activity Roghayeh Siahbalaei, Gholamreza Kavoosi, Raheleh Shakeri (2020)

Tear and serum interleukin-8 and serum CXCL1, CCL2 and CCL5 in sulfur mustard eye-exposed patients Tooba Ghazanfari, Hassan Ghasemi, Roya Yaraee, Mahmoud Mahmoudi, Mohammad Ali Javadi, Z.M Hassan, Fatemeh Heidary, Mahmoud Babaei, Raheleh Shakeri, Ali Mohammad Mohseni Majd, Soghrat Faghihzadeh, Mohammad Reza Soroush (2019)

Alteration in serum levels of ICAM-1 and P-, E- and L-selectins in seriously eye-injured long-term following sulfur-mustard exposure Fatemeh Heidary, Sussan Kaboudanian Ardestani, Hassan Ghasemi, Mohammad Ali Javadi, Mahmoud Mahmoudi, Mohamad Reza Sedighi moghadam, Tooba Ghazanfari, Mohammad Mehdi Naghizadeh, Raheleh Shakeri, Shamsa Shariatpanahi, Faramarz Falahi, Jalaledin Shams, Roya Yaraee (2019)

Physical, thermal, antioxidant and antimicrobial properties of starches from corn, oat, and wheat enriched with Zataria essential oil Zargham Shahrokh, Gholamreza Kavoosi, Raheleh Shakeri (2019)

Cytotoxic and Antioxidant Activities of Crocus pallasii subsp. haussknechtiiCorms Extracts Compared with Crocus sativus Raheleh Shakeri, Jalal Khorshidi, Tayebeh Radjabian, Ali Lashkari, Maliheh Safavi (2019)

Caspase-dependent apoptosis induced by two synthetic halogenated flavanones, 3',7-dichloroflavanone and 3',6-dichloroflavanone, on human breast and prostate cancer cells Maliheh Safavi, Raheleh Shakeri, Sussan Kaboudanian Ardestani, Jamshid Davoodi, Soheila Ajdary, Alireza Foroumadi (2017)

Preparation and characterization of potato starch-thymol dispersion and film as potential antioxidant and antibacterial materials Mina Davoodi, Gholamreza Kavoosi, Raheleh Shakeri (2017)

Apaf-1: Regulation and function in cell death Raheleh Shakeri, َAsma Kheirollahi, Jamshid Davoodi (2017)

Role of the salt bridge between glutamate 546 and arginine 907 inpreservation of autoinhibited form of Apaf-1 Raheleh Shakeri, Saman Hosseinkhani, Marek Jain Los, Jamshid Davoodi, Mayur Vilas Jain, Sussan Kaboudanian Ardestani, Artur Cieslar-Pobuda, Mehrdad Rafat (2015)

Synthesis of Novel 4H-Chromenes Containing a Pyrimidine-2-Thione Function in the Presence of Fe3O4 Magnetic Nanoparticles and Study of Their Antioxidant Activity Mehdi Khoobi, Ali Ramazani, Zahra Hojjati, Raheleh Shakeri, Mehdi Khoshneviszadeh, Sang Woo Joo, Alireza Foroumadi, Abbas Shafiee, Sussan Kaboudanian Ardestani (2014)

In vitro Immunobiological Studies of Novel 5-(5-nitrofuran-2-yl)-1, 3, 4- Thiadiazoles with Piperazinyl-Linked Benzamidine Substituents against Leishmania Major Farzaneh Rezazadeh Marznaki, Raheleh Shakeri, Sussan Kaboudanian Ardestani, Azar Tahghighi, Alireza Foroumadi (2013)

Synthesis and In Vitro Cytotoxic Activity of Novel Chalcone-Like Agents Bahram Letafat, Raheleh Shakeri, Saeed Emami, Saeedeh Noushini, Negar Mohammadhosseini, Alireza Foroumadi, Abbas Shafiee, Aida Letafat, Marjaneh Samadizadeh, Maliheh Safavi, Sussan Kaboudanian Ardestani, Nayyereh Shirkavand (2013)

Conference Papers

مقایسه پروفایل شیمیایی و خواص ضدسرطانی اسانس‌ گیاهان مرزه سهندی و گل اروانه‌ی اورامانی Raheleh Shakeri, Pashiv Mohammadi, Maryam Shiralizadeh, Maliheh Safavi, Jalal Khorshidi (2024)

Cytotoxic activity of doxorubicin in combination with methanolic extract of Crocus pallasii subsp. haussknechtii corms against MDA-MB-231 cancer cell Elaheh Jalali, Raheleh Shakeri, Jalal Khorshidi, Tayebeh Radjabian (2020)

Antioxidant activity and cytotoxicity of tert-butyl p-nitroperbenzoate against MDA-MB-231 and MCF-7 human breast cancer cell lines Hedyeh Zafari, Raheleh Shakeri, Saadi Samadi, Zakaria Vahabzadeh (2020)

Inhibition of MDA-MB-231 cancer cell proliferation by Crocus cancellatus subsp. damascenus corm methanol extract Bahram Savari, Raheleh Shakeri, Jalal Khorshidi (2020)

The growth inhibitory capacity of Thymus daenensis Celak essential oil on MDA-MB-231 cancer cells Sasan Vakili, Raheleh Shakeri, Jalal Khorshidi (2020)

Combinatorial Cytotoxic Effects of Doxorubicin and Stigma Extract of Crocus pallasii subsp. haussknechtii against MCF-7 Human Breast Cancer Cell Line Kimia Rafiei Buzhani, Raheleh Shakeri, Jalal Khorshidi, Tayebeh Radjabian (2019)

Periodic Behavior of Telomerase Activity in Relation to Telomere Length in Some Human Cancers Mehdi Shakeri, Mehrdad Babazadeh, Raheleh Shakeri (2019)

Role of 270 and 271 residues on function of Lampyris turkestanicus luciferase Raheleh Shakeri, Saman Hosseinkhani, Sussan Kaboudanian Ardestani (2014)

Cytotoxic activities of 2-benzylidene-6-(nitrobenzylidene)cyclohexanones against three human cancer cell lines Raheleh Shakeri, Sussan Kaboudanian Ardestani, Alireza Foroumadi (2013)

Anticancer and antioxidant activity of new synthetic chromene derivatives Raheleh Shakeri, Sussan Kaboudanian Ardestani, Abbas Shafiee (2012)

Partial isolation of Natural Compounds as Caspase-9 Inhibitors from Iranian Soil Bacteria Raheleh Shakeri, Mohammad Ali Faramarzi, Jamshid Davoodi, Alireza Foroumadi (2010)

The potential of intracellular extracts of Iranian soil isolates of bacteria on caspase-9 inhibition. Raheleh Shakeri, Mohammad Ali Faramarzi, Jamshid Davoodi (2009)

Theses

بررسی میان‌کنش متوتروکسات با پپسین Hadis Dehfouli, Roohollah Hemmati, Raheleh Shakeri, Khadijeh Pouraghajan Gazafroodi (2024)

.row3_default .researchActivities .researchTypeContent { opacity: 1; position: static; height: initial; } .row3_default .researchActivities .researchActivitiesWrapper .researchTypeTitle { visibility: visible; font-family: Arial; font-size: 1.3rem; transition: background-color .5s, color .5s; display: block; float: left; color: rgb(102, 102, 102); background-color: rgb(255, 255, 255); direction: ltr; text-align: left; padding: .5% 2%; cursor: pointer; border-radius: 5%; margin-top: 1%; } .row3_default .researchActivities .researchTypeContent table .Gv-Empty { text-align: left; direction: ltr; }

Research interests

Anticancer activity of natural products and synthetic agents
Protein engineering
Molecular mechanisms of cell death

Advisor of Biotechnology Society in University of Kurdistan (1397 - present)

Raheleh Shakeri

Education

Courses

Research activities

Research interests

Executive activities

Links