—This paper proposes an IRS-aided design to mitigate the persistent outage floor issue frequently ob served in multi-user full-duplex (FD) cooperative systems. It is assumed that the destination is affected by co-channel interference (CCI). Two antenna modes, namely dynamic antenna mode (DAM) and static antenna mode (SAM), are utilized for M FD relays and N IRS devices, each with K reflecting elements. A combined method for selecting the antenna mode, relay, and IRS devices is employed to enhance overall network performance. The effect of CCI is also investigated for the proposed schemes. For all SNR regions, the diversity gains achieved by DAM and SAM are NK + M and NK + 2M, respectively. The results demonstrate that using IRS devices with a parallel structure provides greater spatial diversity and outperforms traditional FD cooperative systems in the presence of CCI.