CoFe2O4@3D-Network polymers-K22.Pd was synthesized by grafting Kryptofix-22 moieties onto the surface of magnetic 3D-network polymers, followed by a reaction of the nanocomposite with Palladium (II) nitrate. The cavities of the Kryptofix- 22 host material can effectively stabilize the Pd nanoparticles and prevent their aggregation and separation from the surface. Using advanced characterization techniques, such as FT-IR, BET, TGA, FE-SEM, TEM, XRD, EDX, and VSM, thorough understanding of the catalyst structure and morphology was facilitated and confirmed, its expected properties. The catalyst has been efficiently applied to Suzuki reactions and reduction of nitro compound derivatives. Its primary advantages include mild reaction conditions, high efficiency, and shorter reaction times than traditional methods. One of the greatest benefits of this catalyst is its reusability. It can be easily separated from the reaction mixture using a magnetic force and reused for up to five cycles without significant activity loss. This is important for sustainable chemistry, as it reduces waste and potentially lowers costs.