The development of highly efficient and green catalyst for the one-pot synthesis of 5-substituted tetrazole and polyhydroquinoline derivatives is an extremely important and ground challenging area in organic chemistry. In this study, two catalysts were prepared by the immobilization of Ni and Cu on ordered mesoporous silica (SBA- 15) coated with glycine. The proposed catalysts were characterized by FT-IR, XRD, BET, TGA, EDX, and ICP-OES studies and were successfully applied in the synthesis of 5-substituted tetrazoles and polyhydroquinoline derivatives. This designed protocol offers several advantages including the use of commercially available and inexpensive materials, simple procedure, short reaction times, high yield, and easily separable and reusable catalyst.
