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Khaled Azizi

Academic rank: Associate Professor
ORCID:
Education: PhD.
ScopusId: 6506822651
Faculty: Faculty of Science
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Phone:

Research

Title
Conformational Analysis and Intramolecular Bond Strength of Complexes of C6H5NH+ with AT Set: A Quantum Chemical Investigation
Type
Presentation
Keywords
ندارد
Year
2014
Researchers Maryam Malmir ، Khaled Azizi ، Abdolvahab Seif

Abstract

Like most other classes of chemical mutagens, the aromatic amines (ArNH2) are metabolically activated to change the genetic code in DNA[1]. Mutagenic and carcinogenic ArNH2 are present in our environment.They have been identified in food,in cigarette smoke and etc. It has been verified that the metabolism of aromatic and heteroaromatic amines results in nitrenium ions (ArNH+) that can modify the nature and function of nucleobases of DNA[2].In this work we examine the complexes including ArNH+against adenine-thymine (AT)set, as one of the DNA base pairs.