Human casualties and financial losses in the urban texture resulted from the buildings demolitions are among the most important impacts of earthquake in cities. The concept of location vulnerability can be investigated in different categories factors; natural, artificial factors and the combination of both natural factors and human interventions are examples of this type. In order to enhance the power of the decision-making, management, and supervision bodies, the concept of urban vulnerability can be assessed for better governance of the city in future and preparedness for more intelligently operation at the time of crisis. In this study, 10 physical vulnerability criteria of urban texture and data of each criterion for six municipality zones of Tehran metropolitan were collected and were classified into four main factors using functional analysis method. After drawing the zoned vulnerability maps in GIS, using linear regression and with reference to the functional scores, a new ordering of criteria was achieved for prioritization of the programs dealing with the zone vulnerability conditions against earthquake. The final prioritization revealed that the main criteria of building establishment is very important followed by the criteria addressing the rules of the building size and form.