The growth of Epipremnum aureum Lindl. and Andre (‘Golden Pothos’) plants were evaluated using different pot mixtures. Plant growth was measured by 11 parameters: freshness, leaf area, leaf number, mean root length, root number, shoot number, root fresh and dry weight, shoot fresh and dry weight and mean shoot length. Parameters such as freshness, shoot length, shoot fresh and dry weight; root fresh and dry weight and root number were higher in the media containing only coco peat. Shoot number was higher in the medium containing equal leaf-mold:sand mixture compared to the other media. Highest root length and leaf area were obtained in 1:3 peat moss/coco peat mixture. Leaf number was higher in the media containing 3:1 leaf-mold/coco peat mixture. It is concluded that these differences represent a direct effect on the rooting process and that substrate characteristics are of the utmost importance for the quality of rooted cuttings.