The aim of this study was to investigate the role of resistance training (RT) on advanced glycation end products (AGEs) concentrations in postmenopausal women with type II diabetes. Postmenopausal female patients from the Sanandaj Diabetes Association, aged 48-58 years, were randomly assigned to either experimental (n=7) or control (n=8) group. The experimental group has performed a routine program of resistance training for eight weeks, three sessions per week with 70% of one repetition maximum. The control group did not have any type of exercise program during the study. Two-way ANOVA with repeated measures showed that advanced glycation end products’ values in the experimental group (compared with the pre-test) was significantly reduced (p=.014). Similarly, AGEs concentrations were significantly lower in the post-test in the experimental group compared with the control group (p=.000). In addition, fasting blood glucose (FBS) levels in the experimental group after 8-week resistance training was associated with a significant reduction (p=.005). The findings suggest that eight weeks of RT reduced blood glucose concentrations, which lead to decreased levels of advanced glycation end products in postmenopausal women with type II diabetes.