Background: Most athletes tend to experience anything that can improve their performance. ZMA Supplement is special and unique combination of vitamins and minerals that composed of zinc, magnesium, vitamin B6 and aspartate. Methods: 28 male non-athletes with a mean age of 65/1 ± 27/21 years, weight 26/10 ± 24/68 kg, and body mass index 54/2 ± 54/21 kg /m2 volunteers selected randomly, and in a blind design divided to three groups: ZMA, ZMA+ carbohydrate and placebo groups. Results: In muscle strength, the results showed that despite the differences within the group, the more muscles, the differences between the groups was not significant. Anaerobic power in both supplement groups found a similar improvement. Discussion and Conclusion: Findings indicated that regular exercise training alone is able to increase muscle strength in non- athletes and supplementation has little effect. This result is consistent with wilborn and Koehler’s findings (1, 2) and the results are in contrast to brilla (3). Perhaps it is because that ZMA supplementation would be effective for persons that have severe or moderate zinc and magnesium deficiency (2).