Objectives: Nanotechnology is an exciting and rapidly emerging technology [1]. Zinc is also an essential element in virtually all cells of the body and there are more than 300 types of enzymes activity [15]. Due to the increasing production of zinc oxide nanoparticles and its useful applications in biological systems, in this study the effects of zinc oxide nanoparticles on hematological parameters and relative weights of carcass characteristics in laying quails were studied. Materials & Methods: Seventy five laying Japanese quails in a completely randomized design with 5 treatments of female quail (levels ppm 0, 20, 60, 180 of zinc oxide nanoparticles and control group included 60 ppm common form of zinc ) and 5 replicate groups (each repeated three birds per cage) were investigated. An observation using SAS software and statistical analysis using GLM ANOVA and Duncan’s multiple range tests were used to compare means. Results & Conclusion: The results showed hemoglobin, the mean corpuscular hemoglobin (MCH) , the mean corpuscular hemoglobin concentration (MCHC) in treatment 20 ppm (P < 0.05) was significantly lower than in control group, but the MCV, RBC, hematocrit and white blood cells were not significantly different. Also brain weight were significantly decreased (P < 0.05) in treatments 60 and 180 ppm as compared with control group. These results suggest that the common form of zinc can be replaced by zinc oxide nanoparticles in diet of laying Japanese quail.
