This experiment was conducted using 48 doe, 3.5 years, 2 parity, 44±1.2kg body weight and body condition score (BCS)around 3 to investigate the effects of different hormonal and flushing treatments on reproductive performance of Markhoz goats. Animals allocated in 6 groups including 8 doe in each group. Treatments were divided in two categories, hormonal and flushing. Hormonal groups including: group A [Injection of GnRH 5ml)+basal diet]; group B [injection 600 IU of eCG + basal diet]. Flushing groups were: group C [400 grams of barley grain + basal diet], Group D [soybean oil + basal diet], E group [Sunflower oil +basal diet] and the control group F [basal diet]. Flushing continued for 4 weeks in which BCS changed from 2.5 in the beginning to 3 in the end of experimental period. Estrus synchronized using CIDR 18 days before insemination and doe inseminated with fresh semen 48 hours after removal of CIDR. Blood samples collected 2, 48 and 92 hours after remove of CIDR and 20 days after artificial insemination. The SAS software was used for statistical analysis of data. Hormonal and flushing treatments improved reproductive traits such as fertility and kidding rates (P<0.01). Both GnRH injection and fat resources consumption increased the concentration of progesterone in the ovulation and following stages (P<0.05). eCG injection and consumption of barley grain increased the estrogen concentration in follicular phase(P<0.05). Consumption of fat resources in flushing period increased offspring birth weight (average weight 2.9 vs. 2.7 kg) (P<0.01). Among blood metabolites (estrogen, protein, glucose and phosphor), the concentration of estrogen (r= 0.6, P<0.01) and protein (r= 0.29, P<0.05) showed positive and significant correlation with the offspring numbers. Results showed that, both hormonal and flushing treatments significantly increased reproductive performance of Markhoz female goats.
