Sleep and its disorders are still the least understood phenomena in biology. This systematic review aims to identify four personality psychobiological models related to sleep disorders and sexual dysfunction. The literature search for English-language records was conducted on the Web of Science, Scopus, PubMed, ProQuest and Cochrane databases from January 1990 to April 2019. According to the number of studies available related to research variables and heterogeneous designs, the pooled effect size was calculated separately for both case-control and correlation studies using the random-effects method because of the heterogeneity of the studies and use of the I2 measure. The numbers of studies on parasomnias, Restless Legs syndrome, sleep breathing disorders, daytime sleepiness and sexual dysfunction were minimal. However, the present meta-analysis on four studies on insomnia showed that the cases and controls in harm avoidance (HA) are significantly different (p=0.001). Another meta-analysis on 11 studies showed that a significant correlation exists between poor sleep quality assessed using the Pittsburgh Sleep Quality index with negative affect (NA) (z=10.437, p<0.001) and positive affect (PA) (z=-6.826, p<0.001). In addition to the few studies on sleep and sexual disorders, the greater challenge is the wide range of these disorders, making it difficult to perform a comprehensive meta-analysis and draw a conclusion. Generally, NA/PA and HA may play critical roles in sleep quality and insomnia, respectively. These findings and limitations are debatable.
