Silver nanoparticles are emerging as one of the fastest growing product categories in the nanotechnology industry with focus on antibacterial, antifungal and Antivirus activity. This study was conducted to investigate whether the silver nanoparticles would influence the carcass characteristics, some of hematological parameters and antioxidant enzyme activities in laying quail. A total of 60 female quail were randomly divided into 20 experimental cages, three birds in each cage and each treatment was offered to 5 replicates at random, and treatments included 0, 12, 36 and 108 ppm of silver nanoparticles in drinking water from one-day old to 13 weeks age. The results showed that the relative liver weight was decreased in treatments receiving 36 and 108 ppm of silver nanoparticles (p<0.05) and other carcass characteristics have not been affected (p>0.05). The liver enzyme aspartate aminotransferase has been increased dramatically in 108 ppm treatment compared with other treatments and control (p<0.01). Total antioxidant capacity, malondialdehyde formation in liver and serum were significantly increased in two treatments: 36 and 108 ppm, (p<0.05). Base of these results, Silver nanoparticles causes disorders of liver and increases induction of stress oxidative in laying Japanese quails.
