Amines are found in the structure of important pharmacologically active compounds, as well as biologically active for example neurotransmitters. Due to the high importance of amines, several methods have been developed for their synthesis such as the addition reaction of amine compounds 1. Nowadays, numerous organic compounds such as amines were synthesized through the reaction between amid derivatives and imines which the use of immobilized catalysts on various solid supports with the advantage of catalyst separation and recyclization is one of the suitably developed strategies in recent years. Among the different types of used supports in heterogeneous catalysis, mesoporous silica MCM-41 on Fe3O4 has been employed as useful and versatile nanomagnetic catalyst 2,3. The use of boron reagents 1 as a source of aryl through the exchange of aryl groups between boron and metal is one of the most commonly used methods for the arylation of aldehyde 4. In this work, amine derivatives were synthesized by N-arylation of p-toluene sulfonamide 2 in the presence of a nanomagnetic catalyst (MCM-41@Fe3O4) in the optimum condition in excellent yields and short reaction time (Scheme 1). The structure of the catalyst was identified via SEM, EDAX, TGA and, FT-IR techniques, and the prepared products were characterized by melting point and IR, 1HNMR, and 13CNMR spectral analysis.
