Metal-organic frameworks (MOFs) are a category of compounds with both organic and inorganic parts.1 Between these large families, Zr-based MOFs, which also are known as UiO family, have been attracted more attention than the other MOFs because of their high thermal and chemical stability. One of these porous materials, UiO-66, has received remarkable attention due to its easy synthesis, high relative stability, high specific surface area, large porosity and leading properties for a wide range of applications in different fields.2 According to the high surface area feature, UiO-66 can also be used as support. Metal oxide nanoparticles that show great catalytic activity, can simply be loaded in the pores of UiO-66.3 Henry reaction is one of the C-C bond forming reactions in organic synthesis, which produces β-Nitroalcohols.4 In this work, CuO@UiO-66 was prepared by solvothermal method and characterized by several techniques such as FT-IR, XRD, SEM, EDX, TEM, and BET-BJH (Scheme 1). Then, the catalytic activity of CuO@UiO-66 was examined in the Henry reaction and the resulting products were obtained with high yields in short time of reaction (Scheme 2).
