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Title
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three componentreaction between alkyl isocyanidesand dimethyl 1,3-acetonedicarbocxylatein the presence of acetylenic esters:
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Type
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Presentation
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Keywords
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alkyl isocyanides, three componentreaction, dimethyl 1,3-acetonedicarbocxylatein; MCRS
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Abstract
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The design of multicomponent reaction (MCR) is an important field of research in combinatorial chemistry [i]. Because they are one pot reactions, generally MCRS afford good yields and ready operations and are fundamentally different from tow-component reactions in several aspects [2]. Therefore, great efforts have been and still are being made to fined and develop new multicomponent reactions [3]. The chemistry of poly functionalized 4H-pyranes is an ongoing area of interest because of their wide range of applications [4]. We previously reported [5] the synthesis of fused 2amino-4H-pyrane derivatives from the reaction of alkylisocyanides with acetylenic esters in the presence of cyclic i, 3diketones.
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Researchers
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koroush pourdavaee (Third Researcher), Fatemeh Nazem (Second Researcher), Farough Nasiri (First Researcher)
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