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Title synthesis of 3-alkylidene-1,2,3,5,6,7-hexahydro-4H-indol-4-one derivatives in THF-H2O system
Type JournalPaper
Keywords dibenzoyleacetylene, enamino carbonyl compounds, 3-alkylidene pyrroles
Abstract The reaction of dibenzoyleacetylene with cyclic or acyclic enamino carbonyl compounds in water leads to the corresponding 3-alkylidene-2,3-dihydro-1H-pyrrole-2-ol or 3-alkylidene-1,2,3,5,6,7-hexahydro-4H-indol-2-ol derivatives in high yield. When the reactions were carried out in CH2Cl2, yields were lowered and, in some cases, mixtures of products were obtained.
Researchers Hoorieh Djahaniani (Fifth Researcher), Farough Nasiri (Fourth Researcher), Sanaz Souri (Third Researcher), Mehdi Sirouspour (Second Researcher), yavari Issa (First Researcher)